{"id":5781,"date":"2023-08-16T15:50:36","date_gmt":"2023-08-16T06:50:36","guid":{"rendered":"https:\/\/tatsu-blog.jp\/?p=5781"},"modified":"2023-08-16T15:50:36","modified_gmt":"2023-08-16T06:50:36","slug":"20%e6%99%82%e9%96%93%e3%83%95%e3%82%a1%e3%82%b9%e3%83%86%e3%82%a3%e3%83%b3%e3%82%b0%e3%82%92%e3%81%af%e3%81%98%e3%82%81%e3%81%a61%e9%80%b1%e9%96%93%e3%81%8c%e7%b5%8c%e3%81%a3%e3%81%a6%e3%81%97","status":"publish","type":"post","link":"https:\/\/tatsu-blog.jp\/?p=5781","title":{"rendered":"20\u6642\u9593\u30d5\u30a1\u30b9\u30c6\u30a3\u30f3\u30b0\u3092\u306f\u3058\u3081\u30661\u9031\u9593\u304c\u7d4c\u3063\u3066\u3057\u307e\u3063\u305f\u306e\u3067\u3001\u7d50\u679c\u5831\u544a"},"content":{"rendered":"
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\u00a0<\/span><\/div>\n<\/div>\n
\n
\u6b63\u76f4\u30b5\u30d7\u30ea\u304c\u5b9f\u969b\u306b\u52b9\u3044\u3066\u308b\u304b\u3069\u3046\u304b\u306f\u3001<\/span><\/div>\n
<\/div>\n
\u30b5\u30fc\u30c1\u30e5\u30a4\u30f3\u907a\u4f1d\u5b50\u691c\u67fb\u3067Sirt1\u306e\u5024\u3092\u898b\u306a\u3044\u3068\u5206\u304b\u3089\u306a\u3044\u3067\u3059\u3002<\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u30fb\u30fb\u304c\u3001\u8ab0\u3082\u691c\u67fb\u3057\u3066\u308b\u3068\u3044\u3046\u4eba\u304c\u3044\u307e\u305b\u3093\u3002<\/strong><\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u30de\u30b8\u3067\u4e0d\u601d\u8b70\u3053\u306e\u3046\u3048\u306a\u3044\u3067\u3059\u3002\u8b0e\u3059\u304e\u307e\u3059\uff57<\/strong><\/span><\/div>\n<\/div>\n
<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u3060\u304b\u3089\u3053\u306e\u30b5\u30d7\u30ea\u52b9\u3044\u3066\u308b\u306e\uff1f\u307f\u305f\u3044\u306a\u4e8b\u304c\u6c17\u306b\u306a\u308b\u65b9\u306f\u3001<\/span><\/div>\n
<\/div>\n
\u3061\u3083\u3093\u3068\u691c\u67fb\u3057\u305f\u65b9\u304c\u3044\u3044\u3067\u3059\u3002<\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u79c1\u306f\u691c\u67fb\u3092\u5b9a\u671f\u7684\u306b\u3057\u3066\u307e\u3059\u306e\u3067\u3001<\/span><\/div>\n
<\/div>\n
\u4eca\u73fe\u5728\u901a\u5e38\u306e\u4eba\u306e1.3\u500d\u5f31\u3001Sirt1\u306e\u5024\u304c\u9ad8\u3044\u306e\u306f\u5206\u304b\u3063\u3066\u307e\u3059\u3002<\/strong><\/div>\n<\/div>\n
<\/div>\n
\"\"<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u3067\u3059\u304c\u3001\u3053\u308c\u306fNMN\u3067\u306f\u306a\u304f<\/span><\/div>\n
<\/div>\n
\u30c7\u30a2\u30b6\u30d5\u30e9\u30d3\u30f3\u3068\u3044\u3046\u30b5\u30d7\u30ea\u306e\u52b9\u679c\u306a\u6c17\u304c\u3057\u307e\u3059\u3002<\/strong><\/div>\n
<\/div>\n
\u4e00\u5fdcNMN\u3082\u98f2\u3093\u3067\u307e\u3059\u304c<\/span><\/div>\n<\/div>\n
<\/div>\n
\n
\u3068\u306a\u308b\u3068\u3001\u5df7\u3067\u3044\u3046NMN\u306a\u3093\u304b\u3088\u308a<\/span><\/div>\n
\u30c7\u30a2\u30b6\u30d5\u30e9\u30d3\u30f3\u3092\u98f2\u3093\u3060\u65b9\u304c\u3084\u306f\u308a\u52b9\u679c\u306f\u9ad8\u3044\u3068\u3044\u3046\u8a71\u306b\u306a\u308a\u307e\u3059\u304c\u3001<\/span><\/div>\n
\u3061\u3087\u3063\u3068\u6bd4\u8f03\u30c7\u30fc\u30bf\u30fc\u304c\u7121\u3044\u306e\u3067\u5206\u304b\u3089\u306a\u3044\u3067\u3059\u3002<\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u305d\u3082\u305d\u3082\u533b\u7642\u6a5f\u95a2\u3067Sirt1\u306e\u5024\u3092\u8abf\u3079\u3066\u308b\u4eba\u306a\u3093\u3066\u591a\u5206\u6b86\u3069\u3044\u306a\u3044\u306e\u3067\u3001<\/span><\/div>\n
<\/div>\n
\u5468\u308a\u304b\u3089\u306e\u60c5\u5831\u3082\u5f97\u3089\u308c\u307e\u305b\u3093\u306e\u3067\u30b3\u30c4\u30b3\u30c4\u8abf\u3079\u3066\u6bd4\u8f03\u691c\u8a3c\u3057\u3066\u3044\u304f\u3057\u304b\u306a\u3044\u3067\u3059\u306d\u3002<\/span><\/div>\n<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
\n
\n\n\n\n
\u5065\u5eb7\u306f\u30b3\u30f3\u30c7\u30a3\u30f3\u30b7\u30e7\u30f3\u306ePDCA\u30b5\u30a4\u30af\u30eb\u3092\u56de\u3059\u30b2\u30fc\u30e0<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n
\n
<\/div>\n
<\/div>\n
\u305d\u3053\u307e\u3067\u691c\u67fb\u3068\u304b\u3059\u308b\u5fc5\u8981\u3042\u308b\uff1f\u3068\u601d\u308f\u308c\u308b\u65b9\u3082\u591a\u3044\u304b\u3082\u3067\u3059\u304c\u3001<\/strong><\/div>\n
<\/div>\n
<\/div>\n<\/div>\n
\n
\u3053\u308c\u3082\u30de\u30fc\u30b1\u30c6\u30a3\u30f3\u30b0\u3068\u540c\u3058\u3067<\/strong><\/div>\n
<\/div>\n
\u300c\u30b3\u30f3\u30c7\u30a3\u30b7\u30e7\u30f3\u306ePDCA\u300d\u3068\u601d\u3048\u3070\u30b2\u30fc\u30e0\u307f\u305f\u3044\u3067\u9762\u767d\u3044<\/span>\u3067\u3059\u3002<\/strong><\/div>\n<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u4e00\u756a\u81ea\u5206\u306e\u4f53\u306b\u3068\u3063\u3066\u6700\u9069\u306a\u65b9\u6cd5\u306f\u4f55\uff1f\u307f\u305f\u3044\u306a\u7b11<\/span><\/div>\n<\/div>\n
\u00a0<\/span><\/div>\n
<\/div>\n
\n
\u3053\u3053\u307e\u3067\u5065\u5eb7\u610f\u8b58\u304c\u3042\u3063\u3066\u3082\u3001\u6700\u8fd1\u306f\u307b\u307c\u30eb\u30fc\u30c6\u30a3\u30f3\u3067\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u307e\u3059\u3057\u3001<\/span><\/div>\n<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u52ff\u8ad6\u4eba\u304b\u3089\u5916\u98df\u306b\u8a98\u308f\u308c\u307e\u3059\u3068\u884c\u3063\u3066\u697d\u3057\u304f\u98df\u3079\u307e\u3059\u3057\u3001<\/span><\/div>\n
<\/div>\n
\u304a\u9152\u306a\u3093\u304b\u3082\u697d\u3057\u304f\u3067\u3042\u308c\u3070\u98f2\u3093\u3060\u308a\u3057\u307e\u3059\u3002<\/span><\/div>\n<\/div>\n
\n
\u30b7\u30fc\u30b7\u30e3\u3082\u30ac\u30f3\u30ac\u30f3\u5438\u3044\u307e\u3059\u3057\u3002<\/span><\/div>\n<\/div>\n
\u00a0<\/span><\/div>\n
\n
\u3060\u304b\u3089\u30a2\u30b9\u30ea\u30fc\u30c8\u307f\u305f\u3044\u306a\u4e0a\u304b\u3089\u4e0b\u307e\u3067\u5b8c\u74a7\u3092\u76ee\u6307\u3057\u3066\u308b\u8a33\u3067\u306f\u306a\u304f\u3001<\/strong><\/span><\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u6700\u4f4e\u9650\u306e\u65b9\u6cd5\u3067\u6700\u9ad8\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u3059\u308b\u306b\u306f\uff1f\u3068\u3044\u3046\u611f\u899a<\/strong><\/span>\u3067\u3084\u3063\u3066\u308b\u8a33\u3067\u3059\u3002<\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u305d\u306e\u305f\u3081\u306b\u306f\u3001\u30de\u30b8\u3067\u3061\u3083\u3093\u3068\u3057\u305f\u30c7\u30fc\u30bf\u30fc\u3092\u53d6\u3063\u305f\u65b9\u304c\u65e9\u3044\u306e\u3067\u3001<\/span><\/div>\n
<\/div>\n
\u30d5\u30a1\u30af\u30c8\u30c1\u30a7\u30c3\u30af\u3092\u533b\u7642\u6a5f\u95a2\u306b\u884c\u304d\u306a\u304c\u3089\u3084\u308a\u307e\u3059\u3002<\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u9006\u306b\u3044\u3048\u3070\u3001\u5065\u5eb7\u306e\u305f\u3081\u306b\u30b5\u30d7\u30ea\u3084\u5065\u5eb7\u98df\u54c1\u3092\u98df\u3079\u3066\u3044\u305f\u308a\u3001<\/strong><\/span><\/span><\/div>\n
<\/div>\n
\u8b0e\u306e\u5065\u5eb7\u6cd5\u3092\u5b9f\u8df5\u3057\u3066\u3044\u308b\u306e\u306b\u3001<\/strong><\/span><\/div>\n
<\/div>\n
\u30d5\u30a1\u30af\u30c8\u30c1\u30a7\u30c3\u30af\u3057\u306a\u3044\u4eba\u306e\u6c17\u6301\u3061\u306f\u3055\u3063\u3071\u308a\u308f\u304b\u308a\u307e\u305b\u3093\u3002<\/strong><\/span><\/div>\n<\/div>\n
<\/div>\n
\u00a0<\/span><\/div>\n
\n
\u591a\u5206\u3001\u3053\u3046\u3044\u3046\u4eba\u9054\u304c\u4fe1\u3058\u308b\u306e\u306f\u4f53\u611f\u306a\u3093\u3060\u3068\u601d\u3044\u307e\u3059\u304c\u3001<\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u5143\u3005\u4f53\u304c\u60aa\u3044\u4eba\u304c\u3061\u3087\u3063\u3068\u30d7\u30e9\u30b9\u306b\u306a\u308b\u306e\u306f\u5f53\u305f\u308a\u524d<\/span>\u3060\u3068\u601d\u3046\u3093\u3067\u3059\u3088\u306d\u3002<\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u79c1\u306e\u5834\u5408\u3001\u304b\u306a\u308aPDCA\u3092\u56de\u3057\u3066\u3044\u3066\u3001<\/span><\/div>\n
\u4eca\u3067\u306f\u30d7\u30e9\u30b9\u3092\u3088\u308a\u30d7\u30e9\u30b9\u306b\u3057\u3066\u3044\u304d\u305f\u3044\u3063\u3066\u611f\u899a\u3067\u3059\u3002<\/span><\/div>\n
<\/div>\n
\uff08\u597d\u304d\u306a\u98df\u3079\u7269\u3082\u98df\u3079\u305f\u3044\u3057\u3001\u5065\u5eb7\u306b\u305d\u3053\u307e\u3067\u610f\u8b58\u5411\u3051\u306a\u304f\u3066\u3082\u5143\u6c17\u306b\u751f\u304d\u305f\u3044\u3002\u305d\u306e\u305f\u3081\u306b\u4e00\u756a\u3044\u3044\u65b9\u6cd5\u306f\uff1f\u3092\u8003\u3048\u7d9a\u3051\u3066\u307e\u3059\uff09<\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u305d\u3046\u3044\u3046\u8a33\u3067\u3001\u8b0e\u306e\u5065\u5eb7\u6cd5\u3084\u8b0e\u306e\u30b5\u30d7\u30ea\u3092\u98f2\u3093\u3067\u308b\u4eba\u306f\u3001<\/span><\/div>\n
<\/div>\n
\u30d5\u30a1\u30af\u30c8\u30c1\u30a7\u30c3\u30af\u306f\u3057\u305f\u65b9\u304c\u3044\u3044\u3067\u3059\u3002<\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u4e00\u756a\u7c21\u5358\u306a\u306e\u306f\u533b\u7642\u6a5f\u95a2\u306b\u3044\u3063\u3066\u3001\u8840\u6db2\u691c\u67fb\u304f\u3089\u3044\u304b\u3089\u59cb\u3081\u308b\u306e\u304c\u3088\u3044\u3068\u601d\u3044\u307e\u3059\u3002<\/strong><\/div>\n<\/div>\n
\u00a0<\/span><\/div>\n
\n
\u3067\u3082\u3001\u3053\u3046\u3044\u3046\u30d5\u30a1\u30af\u30c8\u30c1\u30a7\u30c3\u30af\u3057\u306a\u3044\u4eba\u304c\u5c71\u307b\u3069\u3044\u308b\u304b\u3089\u3053\u305d\u3001<\/span><\/div>\n
<\/div>\n
\u540c\u6642\u306b\u3060\u304b\u3089\u3053\u305d\u30b5\u30d7\u30ea\u306a\u3069\u306e\u30d3\u30b8\u30cd\u30b9\u304c\u6210\u308a\u7acb\u3064\u306e\u3067\u3057\u3087\u3046\u306d\u3002<\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u7121\u77e5\u306a\u4eba\u9054\u306f\u30ad\u30e3\u30c3\u30c1\u30b3\u30d4\u30fc\u3060\u3051\u3067\u8cb7\u3063\u3066\u3044\u304f\u306e\u3067\u3001\u4e2d\u8eab\u306f\u3069\u3046\u3067\u3082\u3044\u3044\u306e\u3067\u3059\u3002<\/span><\/div>\n<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u30de\u30fc\u30b1\u30c6\u30a3\u30f3\u30b0\u3092\u5ef6\u3005\u3084\u3063\u3066\u3044\u304f\u3068\u3001\u3053\u3046\u3044\u3046\u4e8b\u306b\u3042\u305f\u308b\u4e8b\u304c\u3042\u307e\u308a\u306b\u3082\u591a\u3059\u304e\u3066\u3001<\/strong><\/div>\n
<\/div>\n<\/div>\n
\n
\u672c\u5f53\u306b\u4eba\u9593\u3063\u3066\u77db\u76fe\u3068\u30d0\u30b0\u3060\u3089\u3051\u3060\u306a\u30fc\u3068\u611f\u3058\u307e\u3059\u3002<\/strong><\/div>\n
<\/div>\n<\/div>\n
\n
\u305d\u3093\u306a\u8a33\u3067\u5831\u544a\u3067\u3057\u305f\u3002<\/span><\/div>\n<\/div>\n
<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\n\n\n\n
\u304a\u307e\u3051<\/strong><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n
\n
\u3061\u306a\u307f\u306b\u6c34\u3092\u6700\u8fd11\u65e53.7\u30ea\u30c3\u30c8\u30eb\u4ee5\u4e0a\u98f2\u3080\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/span><\/div>\n
<\/div>\n
\u30a2\u30e1\u30ea\u30ab\u533b\u5b66\u7814\u7a76\u6240\uff08IOM\uff09\u3067\u305d\u306e\u4f4d\u5fc5\u8981\u3060\u3068\u3044\u3046\u4e8b\u304c\u3044\u308f\u308c\u3066\u305f\u306e\u3067\u3001\u306a\u3093\u3068\u306a\u304f\u3084\u3063\u3066\u307e\u3059\u3002<\/span><\/div>\n
<\/div>\n
\u4eca\u306e\u6240\u601d\u3063\u305f\u3088\u308a\u3081\u3061\u3083\u304f\u3061\u3083\u3044\u3044\u3067\u3059\u3002<\/span><\/div>\n
<\/div>\n<\/div>\n
\n
\u00a0<\/span><\/div>\n<\/div>\n
\n
\u79c1\u304c\u4f7f\u3063\u3066\u308b\u65ad\u98df\u30c8\u30e9\u30c3\u30ab\u30fc\u3068\u3044\u3046\u30a2\u30d7\u30ea\u3060\u3068\u3001<\/span><\/div>\n
<\/div>\n
\u3069\u306e\u304f\u3089\u3044\u6c34\u3082\u98f2\u3093\u3060\u304b\u30c1\u30a7\u30c3\u30af\u3067\u304d\u308b\u306e\u3067\u610f\u5916\u3068\u4f7f\u3048\u308b\u30a2\u30d7\u30ea\u3067\u3059\u3002<\/span><\/div>\n<\/div>\n
<\/div>\n
\"\"<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
\n
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